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Boost — Morning Activation

Prime your brain for peak output. Boost delivers the raw materials and enzymatic support your cholinergic and dopaminergic systems need to fire on all cylinders — right when your circadian biology is primed for cognitive performance.
The first hours after waking represent a neurochemical window. Cortisol peaks (the cortisol awakening response), acetylcholine sensitivity is high, and dopaminergic circuits are ready for activation. Boost is engineered to capitalize on this window — not fight against it.

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What Boost Delivers

Sharp Focus

Enhanced attention, reduced distractibility, and the ability to lock onto complex tasks for extended periods.

Verbal Fluency

Words come easier. Ideas articulate faster. The tip-of-tongue phenomenon fades.

Mental Drive

The motivation to start hard tasks — not just the capacity to do them. Dopaminergic activation that moves you from intention to action.

Working Memory

Hold more information in mind simultaneously. Manipulate concepts, see connections, solve problems.

Learning Speed

Accelerated encoding of new information. What you study in the morning sticks better.

Neuroplasticity

Long-term structural support for synaptic health, not just acute performance enhancement.

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The Science of Morning Cognition

Your brain doesn’t wake up in a single moment — it phases into full operation over 60-90 minutes. During this window:
1

Cortisol Awakening Response (CAR)

Cortisol surges 50-75% in the first 30-45 minutes after waking. This isn’t stress — it’s your body’s ignition sequence, mobilizing energy and priming alertness.
2

Cholinergic Activation

Acetylcholine systems shift from the diffuse activity of sleep to the focused, task-oriented signaling of wakefulness. This transition determines morning mental clarity.
3

Dopaminergic Readiness

Dopamine circuits, refreshed by sleep, are primed for reward-seeking and goal-directed behavior. The motivation to tackle your hardest work is highest now.
4

Adenosine Clearance

Sleep has cleared adenosine (the molecule that makes you drowsy). You’re starting with a clean slate — no sleep pressure competing for attention.
Boost amplifies each of these natural processes rather than overriding them.

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Complete Ingredient Breakdown

What it does: Provides choline for acetylcholine synthesis while simultaneously delivering uridine — a nucleotide that supports dopamine receptor density and phospholipid membrane synthesis.Why this dose: 250mg provides meaningful cognitive enhancement without the potential for cholinergic overload when combined with Alpha-GPC. The Cognizin® form is the most clinically-validated CDP-Choline, with human trials demonstrating:
  • Improved attention and psychomotor speed
  • Enhanced memory performance
  • Increased brain ATP levels (+14%)
  • Elevated phosphocreatine (+7%)
Mechanism pathway:
CDP-Choline → Choline + Cytidine
                ↓           ↓
         Acetylcholine   Uridine → Phosphatidylcholine
                              ↓
                    Dopamine receptor density ↑
Synergy: CDP-Choline’s uridine component enhances dopamine receptor expression, amplifying the effects of L-Tyrosine in the same formula.
What it does: The highest-bioavailability choline source, delivering choline directly across the blood-brain barrier for rapid acetylcholine synthesis.Why this dose: 300mg provides acute cholinergic enhancement without the GI distress sometimes seen at higher doses. Combined with CDP-Choline, total choline delivery is optimized for both speed (Alpha-GPC) and sustained effect (CDP-Choline).Unique benefits:
  • Fastest choline delivery to CNS
  • Supports growth hormone release (particularly relevant for morning dosing)
  • Membrane phospholipid donor (phosphatidylcholine precursor)
Research highlight: Alpha-GPC has demonstrated cognitive benefits in both young, healthy subjects and age-related cognitive decline — suggesting it enhances a fundamental bottleneck rather than compensating for pathology.
TMAO consideration: Choline can be converted to TMAO by gut bacteria. By splitting choline delivery across two sources and timing Boost for morning (when gut bacteria are less active), we minimize this concern. Occasional users need not worry; daily users should ensure adequate fiber intake.
What it does: Direct precursor to dopamine, norepinephrine, and epinephrine — the catecholamine neurotransmitters that drive motivation, focus, and stress resilience.Why this dose: 500mg is the minimum effective dose for cognitive enhancement in demanding situations. Higher doses (2g+) are sometimes used but offer diminishing returns and can cause jitteriness.When tyrosine shines:
  • Sleep deprivation (protects cognitive function)
  • Acute stress (replenishes depleted catecholamines)
  • Demanding cognitive tasks (working memory, multitasking)
  • Cold exposure (supports thermogenic response)
Mechanism pathway:
L-Tyrosine → L-DOPA → Dopamine → Norepinephrine → Epinephrine
         (TH + BH4)  (AADC + B6)   (DBH + Vit C)    (PNMT + SAMe)
Rate-limiting reality: Tyrosine conversion to L-DOPA via tyrosine hydroxylase (TH) is the rate-limiting step. This enzyme is regulated by catecholamine levels — meaning tyrosine supplementation is most effective when catecholamines are depleted (stress, sleep loss, demanding work).
What it does: Reversibly inhibits acetylcholinesterase (AChE), the enzyme that breaks down acetylcholine. This prolongs acetylcholine signaling in the synaptic cleft.Why this dose: 100mcg is a conservative, well-tolerated dose that provides meaningful AChE inhibition without the side effects (nausea, bradycardia) seen at higher doses. The long half-life (10-14 hours) means once-daily dosing is appropriate.Key properties:
  • Highly selective for AChE (minimal BuChE inhibition)
  • Excellent blood-brain barrier penetration
  • Neuroprotective against glutamate excitotoxicity
  • May support neurogenesis via BDNF
Cycling consideration: Due to the long half-life and potent AChE inhibition, some users prefer to cycle Huperzine A (5 days on, 2 days off). Boost is designed to be effective with daily use, but listen to your body.
Interaction alert: Huperzine A should not be combined with pharmaceutical acetylcholinesterase inhibitors (donepezil, rivastigmine, galantamine) or drugs with anticholinergic properties.
What it does: Stimulates Nerve Growth Factor (NGF) synthesis via unique compounds called hericenones (fruiting body) and erinacines (mycelium). NGF supports neuronal health, synaptic plasticity, and potentially neurogenesis.Why this dose: 500mg of a quality extract (containing both hericenones and erinacines) provides meaningful NGF support. This is a long-term neuroplasticity play — effects build over weeks to months.Research highlights:
  • Improved cognitive function in mild cognitive impairment (Mori 2009)
  • Reduced anxiety and depression scores (Nagano 2010)
  • Enhanced nerve regeneration in animal models
  • Unique among nootropics for structural brain support
Onset expectations:
  • Acute effects: Subtle (some report mild clarity)
  • 2-4 weeks: Emerging cognitive benefits
  • 8-16 weeks: Full neuroplasticity effects
Patience pays: Lion’s Mane isn’t a stimulant — it’s an investment in brain infrastructure. The benefits compound over time.
What it does: Provides essential cofactors for neurotransmitter synthesis, methylation, and energy metabolism — in their active, bioavailable forms.
VitaminFormRole in Boost
B6P-5-PAADC cofactor (DOPA → Dopamine)
B95-MTHFMethylation; BH4 regeneration
B12MethylcobalaminMethylation; nerve function
B1BenfotiamineGlucose metabolism; ATP
B2Riboflavin-5-PMTHFR cofactor; ETC Complex II
B5PantethineAcetyl-CoA synthesis
Why methylated forms: Up to 40% of the population has MTHFR polymorphisms that impair folate metabolism. Methylated B-vitamins bypass this bottleneck, ensuring the cofactors actually work.

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How to Use Boost

Timing

Take with breakfast, ideally within 1 hour of waking. The cholinergic and dopaminergic enhancement aligns with your natural cortisol awakening response.

With Food

Fat-soluble components (Alpha-GPC, Lion’s Mane) absorb better with dietary fat. A breakfast containing eggs, avocado, or nuts is ideal.

Consistency

Daily use allows Lion’s Mane and B-vitamins to build cumulative effects. Acute benefits from choline and tyrosine are noticeable from day one.

Stacking

Boost is designed to work with Sustain (midday) and Recover (evening). Avoid additional cholinergics or stimulants for the first week while you calibrate.

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What to Expect

  • Noticeable increase in mental clarity within 60-90 minutes
  • Improved focus and attention span
  • Easier word retrieval and verbal expression
  • Possible mild increase in motivation/drive

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Synergies Within All Systems Go

Boost → Sustain Handoff

Boost’s cholinergic activation depletes choline over the morning. Sustain’s phosphatidylserine supports membrane integrity while Ashwagandha manages any cortisol overshoot from intense focus.

Recover → Boost Preparation

Recover’s glycine and magnesium ensure deep sleep, which clears adenosine and restores dopamine receptor sensitivity — setting up Boost to work optimally the next morning.

All Systems Go Overview

See how Boost fits into the complete daily optimization system.

Sustain

The midday formula that maintains momentum after Boost.

Recover

Evening restoration that prepares you for tomorrow’s Boost.
Morning is leverage. The cognitive work you do in your first 4 hours often determines the trajectory of your entire day. Boost ensures those hours count.