Optimize Your BiologyAccomplish Your Mission
Explore Systems
Discover our cognitive optimization formulas
Read the Science
Deep-dive into ingredient mechanisms
Method
We don’t chase trends or proprietary blends. Every formula starts with biology, validates with evidence, and optimizes for real outcomes.
Map the Biology
Map the Biology
Identify the biological systems that govern cognitive performance: neurotransmitter pathways, circadian rhythms, cellular energetics, and stress response axes. Understand what needs optimization before reaching for compounds.
Analyse Ingredients
Analyse Ingredients
Evaluate each compound through the lens of mechanism, bioavailability, safety, and synergy. No ingredient enters a formula without clear evidence and a defined role. Our Ingredient Taxonomy classifies 200+ compounds by biological mechanism.
Formulate Systems
Formulate Systems
Combine compounds into coherent systems that work with your biology across the circadian cycle. Optimize for synergy, minimize redundancy, and avoid antagonistic interactions. The result: formulas that perform.
Systems
All Systems Go™
Complete Daily Protocol
The flagship cognitive optimization stack. Three formulas synchronized to your circadian biology.
Boost
Morning ActivationCDP-Choline · L-Tyrosine · Creatine · PQQ · SalidrosideWake up sharp, not wired
Sustain
Daytime PerformanceCDP-Choline · Phosphatidylserine · ParaxanthineAll-day cognitive endurance
Recover
Evening RecoveryGlycine (3g) · Magnesium · Apigenin · L-TheanineSleep deep, wake restored
Neuraldrink™
Circadian Functional Beverages
Sol
Daytime FormulaParaxanthine + Creatine + AdaptogensClean energy without the crash. Designed for sustained cognitive output.
Luna
Nighttime FormulaGlycine (3g) + Magnesium + Apigenin3g Glycine triggers a 0.3°C core temp drop—your body’s natural sleep signal. No sedation, no grogginess.
Performance Stacks
ParaCaffeine +™
Caffeine EvolvedParaxanthine delivers 2.2x higher A2A receptor affinity than caffeine with a shorter half-life and zero anxiogenic metabolites. Clean focus, rapid clearance. No jitters · No crash · Sleep-friendly
Sprint™
Acute PerformanceMaximum cholinergic drive + adenosine antagonism for demanding cognitive tasks. Reserved for when you need peak output. High-intensity · Occasional use
Manuals
Deep Documentation
Ingredient Manual
200+ Compounds ClassifiedOur comprehensive taxonomy organizes every bioactive compound by mechanism of action. Understand what you’re taking and why.
Neurotransmitters · Bioenergetics · Sleep · Adaptogens
Browse by Mechanism
12 Biological DomainsFrom cholinergic compounds to longevity interventions. Find ingredients by the system they target.
Cholinergic · GABAergic · Mitochondrial · HPA Axis · Circadian
Featured Ingredients
Paraxanthine
Caffeine’s clean metabolite
Glycine
Thermoregulatory sleep
PQQ
Mitochondrial biogenesis
Salidroside
Precision adaptogen
FAQ
Which system should I start with?
Which system should I start with?
For most people: Start with ParaCaffeine +™ as a drop-in caffeine replacement. It’s the easiest entry point with immediate benefits.For comprehensive optimization: The All Systems Go™ stack provides morning-to-night coverage with Boost → Sustain → Recover.For sleep issues: Luna (from Neuraldrink™) targets sleep onset through thermoregulation—a mechanism-first approach that doesn’t rely on sedation.
Can I combine systems?
Can I combine systems?
Yes—they’re designed for it. Example protocols:
- Minimal: ParaCaffeine +™ only (replace your morning coffee)
- Focus Stack: ParaCaffeine +™ → Sustain (morning → afternoon)
- Full Protocol: Boost → Sustain → Recover (complete circadian coverage)
- Event Day: Sprint™ (occasional high-demand situations)
What makes NTRPX different?
What makes NTRPX different?
- Mechanism-first design — We start with biology, not ingredients
- Circadian synchronization — Formulas match your daily rhythm
- Full transparency — Every ingredient, dose, and rationale documented
- No proprietary blends — You know exactly what you’re getting
Community
Discord
Join the community for protocol discussions, stack optimization, and direct access to the team.
GitHub
Our research, formulations, and documentation are open. Contribute, review, or fork.