NTRPX Meta System™
Systems
4 Integrated Systems
All Systems Go™ · Neuraldrink™ · ParaCaffeine +™ · Sprint™
Subsystems
7 Targeted Formulations
Boost · Sustain · Recover · Sol · Luna · ParaCaffeine + · Sprint
Biological Domains
12 Optimized Pathways
Every system governing human performance
Core Principle
Circadian Synchronization
Right compounds at right times
Executive Summary
The NTRPX Meta System™ is the most comprehensive, synergistic supplementation architecture ever conceived — engineered from first principles to optimize every domain of human biological performance. This is not a collection of supplements. It is a unified system where every ingredient, every dose, and every timing decision has been made with full awareness of every other component. The result:- Standalone viability: Each subsystem works independently
- Combined optimization: Full protocol exceeds sum of parts
- Zero antagonisms: No ingredient conflicts with another
- Maximum synergy: Compounds amplify each other’s effects
- Circadian synchronization: Biology-matched timing
- Complete coverage: All 12 biological domains addressed
Design Philosophy: We don’t formulate products, then figure out how they work together. We map the complete biological terrain first, identify every pathway that governs human performance, then engineer a unified system where each component plays a defined role. Redundancy is eliminated. Synergies are maximized. Antagonisms are impossible.
System Hierarchy
The 12 Biological Domains
Complete Domain Map & Coverage Matrix
Complete Domain Map & Coverage Matrix
The NTRPX Meta System™ systematically optimizes 12 biological domains. Every ingredient maps to specific domains, ensuring complete coverage without wasteful overlap.
Domain Coverage Matrix
| Domain | Boost™ | Sustain™ | Recover™ | Sol™ | Luna™ | ParaCaffeine +™ | Sprint™ |
|---|---|---|---|---|---|---|---|
| 1. Cholinergic | ★★★★ | ★★★★ | ★ | ★ | — | ★★ | ★★★★★ |
| 2. Dopaminergic | ★★★★★ | ★★ | — | ★★ | — | ★★★ | ★★★★★ |
| 3. Serotonergic | ★★ | ★★★ | ★★ | ★ | ★ | ★ | — |
| 4. GABAergic | — | ★ | ★★★★★ | — | ★★★★★ | — | — |
| 5. Mitochondrial | ★★★★★ | ★★★ | ★★★ | ★★★★ | ★★ | ★★ | ★★★ |
| 6. ATP Systems | ★★★★★ | ★★★ | ★★ | ★★★★★ | ★★ | ★★★ | ★★★★ |
| 7. NAD+ Metabolism | ★★★ | ★★ | ★★★★★ | ★★ | ★★★ | — | ★★ |
| 8. HPA Axis | ★★★★ | ★★★ | ★★★ | ★★★ | ★★ | ★★ | ★ |
| 9. Circadian | ★★★★ | ★★★ | ★★★★★ | ★★★ | ★★★★★ | ★★ | ★ |
| 10. Methylation | ★★★★★ | ★★★ | ★★★ | ★★ | ★★ | ★★ | ★★ |
| 11. Neuroprotection | ★★★★★ | ★★★★ | ★★★ | ★★★ | ★★ | ★★ | ★★★ |
| 12. Cellular Repair | ★★★ | ★★ | ★★★★★ | ★★ | ★★★★ | — | — |
Reading the Matrix: ★★★★★ = Primary target with maximum support. — = Intentionally excluded to maintain circadian appropriateness. Notice how GABAergic compounds concentrate in evening formulas (Recover™, Luna™), while dopaminergic activation is morning-weighted (Boost™).
Master Ingredient Registry
Complete Ingredient Catalog by Mechanism
Complete Ingredient Catalog by Mechanism
All Ingredients in the NTRPX Meta System™
Every compound has been evaluated, selected, and placed based on mechanism, evidence, bioavailability, safety, and synergy with the complete system.🧠 Neurotransmitter Systems
| Ingredient | Form | Primary Systems | Mechanism | Evidence Tier |
|---|---|---|---|---|
| CDP-Choline | Cognizin® | Boost™, Sustain™ | Choline + uridine donor; ACh synthesis, membrane support | TIER 1 |
| Alpha-GPC | 50% | Sprint™ only | Rapid choline delivery; high bioavailability | TIER 2 |
| Huperzine A | 1% extract | Sprint™ only | Acetylcholinesterase inhibitor; amplifies ACh | TIER 2 |
| L-Tyrosine | NALT | Boost™, Sol™ | Dopamine/norepinephrine precursor | TIER 1 |
| L-Theanine | Suntheanine® | Sustain™, Recover™, ParaCaffeine +™ | Alpha waves; GABA/glutamate balance | TIER 1 |
| Apigenin | 98% extract | Recover™, Luna™ | CD38 inhibition; anxiolytic; NAD+ preservation | TIER 2 |
| Paraxanthine | enfinity® | Sustain™, Sol™, ParaCaffeine +™ | A2A antagonism 2.2×; no anxiogenic metabolites | TIER 2 |
⚡ Bioenergetics
| Ingredient | Form | Primary Systems | Mechanism | Evidence Tier |
|---|---|---|---|---|
| Creatine | Creapure® Monohydrate | Boost™, Sol™ | Phosphocreatine buffer; cognitive + physical ATP | TIER 1 |
| PQQ | BioPQQ® | Boost™ | Mitochondrial biogenesis via PGC-1α; CREB activation | TIER 2 |
| CoQ10 | Kaneka Ubiquinol | Boost™ | Electron transport chain; existing mito efficiency | TIER 1 |
| Cordyceps | CS-4 / militaris | Sol™ | Oxygen utilization; AMPK; adenosine analog | TIER 2 |
| NR | Niagen® | Recover™ | NAD+ precursor; sirtuin activation | TIER 2 |
🌿 Adaptogens & Herbs
| Ingredient | Form | Primary Systems | Mechanism | Evidence Tier |
|---|---|---|---|---|
| Rhodiola/Salidroside | 3% salidroside | Boost™, Sol™ | MAO-B inhibition; HPA modulation; fatigue resistance | TIER 2 |
| Lion’s Mane | Fruiting body + mycelium | Boost™ | NGF/BDNF stimulation; neuroplasticity | TIER 2 |
| Ashwagandha | KSM-66® or Sensoril® | Sustain™ | Cortisol reduction; GABAergic; adaptogenic | TIER 1 |
| Bacopa | BaCognize® 45% bacosides | Sustain™ | Memory consolidation; serotonergic; antioxidant | TIER 1 |
| Saffron | affron® 3.5% lepticrosalides | Sustain™ | Serotonin reuptake; mood; neuroprotection | TIER 2 |
😴 Sleep & Circadian
| Ingredient | Form | Primary Systems | Mechanism | Evidence Tier |
|---|---|---|---|---|
| Glycine | Pharmaceutical grade | Recover™, Luna™ | NMDA → hypothalamus → core temp ↓0.3°C | TIER 1 |
| Magnesium L-Threonate | Magtein® | Recover™ | Brain-penetrant Mg; synaptic density; sleep quality | TIER 2 |
| Magnesium Glycinate | Chelated | Recover™, Luna™ | GABA potentiation; relaxation; additional glycine | TIER 1 |
| Taurine | Pharmaceutical grade | Recover™ | GABA-A agonist; osmoregulation; inhibitory tone | TIER 2 |
🏗️ Structural & Cellular
| Ingredient | Form | Primary Systems | Mechanism | Evidence Tier |
|---|---|---|---|---|
| Phosphatidylserine | Sharp-PS® (sunflower) | Sustain™ | Membrane fluidity; cortisol modulation; receptor density | TIER 1 |
| DHA | Life’s DHA® (algal) | Sustain™ | Neuronal membrane; anti-inflammatory; synaptic | TIER 1 |
| EPA | Algal | Sustain™ | Anti-inflammatory; cardiovascular; mood | TIER 1 |
❤️ Cardiovascular / Nitric Oxide
| Ingredient | Form | Primary Systems | Mechanism | Evidence Tier |
|---|---|---|---|---|
| L-Citrulline | Free form | Sol™ | Arginine precursor; sustained NO; blood flow | TIER 1 |
| Nitrosigine® | Arginine silicate inositol | Sol™ (alternative) | Stabilized arginine; rapid NO | TIER 2 |
🧬 Essential Nutrients (B-Vitamins — Active Forms Only)
| Vitamin | Form | Primary Systems | Rationale |
|---|---|---|---|
| B1 | Benfotiamine + TTFD | Boost™, Sustain™ | Benfotiamine peripheral; TTFD CNS-penetrant |
| B2 | Riboflavin-5’-Phosphate (R5P) | All Systems Go™ | Active coenzyme; no conversion needed |
| B3 | Nicotinamide Riboside (NR) | Recover™ | NAD+ precursor; superior to niacin/NMN |
| B5 | D-Calcium Pantothenate | All Systems Go™ | CoA synthesis; standard form effective |
| B6 | Pyridoxal-5’-Phosphate (P5P) | All Systems Go™ | ONLY acceptable form; pyridoxine neurotoxic |
| B7 | D-Biotin | Boost™ | Standard form; avoid >1000mcg (lab interference) |
| B9 | L-5-MTHF (Quatrefolic®) | All Systems Go™ | Active folate; bypasses MTHFR; NO folic acid |
| B12 | Methylcobalamin + Adenosylcobalamin | All Systems Go™ | Both coenzyme forms; complete B12 support |
🔋 Electrolytes (Neuraldrink™)
| Electrolyte | Form | Sol™ | Luna™ | Rationale |
|---|---|---|---|---|
| Sodium | Citrate + Pink Himalayan | 1000mg | 300mg | Primary hydration driver; lower at night |
| Potassium | Citrate | 500mg | 300mg | Intracellular balance; muscle function |
| Magnesium | Citrate + Glycinate | 100mg | 200mg | Higher at night for sleep |
| Chloride | From sodium chloride | 400mg | 150mg | Fluid balance |
| Calcium | Citrate | 100mg | 50mg | Nerve transmission |
| Zinc | Picolinate | — | 15mg | Nighttime immune; sleep regulation |
Ingredients Evaluated but EXCLUDED
Ingredients Evaluated but EXCLUDED
Compounds Considered but Not Included
The following ingredients were rigorously evaluated but excluded from the NTRPX Meta System™ for specific reasons:| Ingredient | Reason for Exclusion |
|---|---|
| Methylene Blue | Narrow therapeutic window; MAOI interactions; photosensitivity; requires medical supervision; not appropriate for consumer supplement |
| L-Arginine | Poor oral bioavailability; extensive first-pass metabolism; L-Citrulline superior for NO production |
| Folic Acid | Synthetic; requires multi-step conversion; 30%+ population has MTHFR variants; masks B12 deficiency; L-5-MTHF universally superior |
| Pyridoxine HCl | Documented neurotoxicity risk; competitive inhibition of P5P at high doses; P5P is the only acceptable B6 form |
| Cyanocobalamin | Requires conversion; contains cyanide moiety; methylcobalamin + adenosylcobalamin provide direct coenzyme forms |
| Caffeine | Produces anxiogenic metabolites (theophylline); longer half-life than paraxanthine; paraxanthine is the active metabolite with 2.2× A2A affinity |
| Melatonin | Creates dependency; suppresses endogenous production; glycine’s thermoregulatory mechanism is superior for sleep onset |
| Alpha-GPC (daily use) | 2021 study: 46% increased stroke risk with 10+ year use; CDP-Choline preferred for chronic use; Alpha-GPC reserved for acute/occasional Sprint™ |
| Choline Bitartrate | Poor brain bioavailability; doesn’t cross BBB efficiently; CDP-Choline and Alpha-GPC superior |
| Racetams | Regulatory uncertainty; limited clinical evidence in healthy populations; mechanism overlap with established nootropics |
| Phenylpiracetam | Banned by WADA; limited availability; unclear long-term safety |
| Modafinil | Prescription-only; not appropriate for supplement formulation |
Circadian Synchronization Protocol
24-Hour Optimization Architecture
24-Hour Optimization Architecture
The Circadian Imperative
Human biology oscillates in predictable 24-hour cycles. Cortisol peaks in morning. Melatonin rises at night. Neurotransmitter receptor sensitivity shifts throughout the day. Core body temperature follows a precise rhythm that signals sleep onset.A supplementation system that ignores circadian biology is fundamentally flawed.Circadian Ingredient Placement Matrix
| Ingredient Category | Morning ☀️ | Midday 🌤️ | Evening 🌙 | Rationale |
|---|---|---|---|---|
| Dopamine Precursors (Tyrosine) | ✓✓✓ | ✓ | ✗ | Aligns with cortisol; evening use disrupts sleep architecture |
| Cholinergics (CDP-Choline) | ✓✓✓ | ✓✓✓ | ✓ | Supports waking cognition; lower evening dose acceptable |
| Adenosine Antagonists (Paraxanthine) | ✓✓ | ✓✓ | ✗ | t½ 3-4h; must clear before sleep; 2PM cutoff recommended |
| Activating Adaptogens (Rhodiola) | ✓✓✓ | ✓✓ | ✗ | Morning stress resilience; may interfere with wind-down |
| Calming Adaptogens (Ashwagandha) | ✓ | ✓✓ | ✓ | GABAergic; acceptable anytime but emphasize midday |
| Memory Herbs (Bacopa, Lion’s Mane) | ✓✓ | ✓✓✓ | ✓ | Chronic effects; timing less critical |
| GABAergics (Theanine, Taurine, Apigenin) | ✓ | ✓ | ✓✓✓ | Low doses OK anytime; concentrate evening for sleep |
| Thermoregulatory (Glycine 3g) | ✗ | ✗ | ✓✓✓ | Specifically triggers sleep via core temp ↓0.3°C |
| Magnesium Threonate | ✓ | ✓ | ✓✓✓ | Brain-penetrant; emphasize evening for sleep quality |
| Magnesium Glycinate | ✓ | ✓ | ✓✓✓ | GABA potentiation; emphasize evening |
| PQQ + CoQ10 | ✓✓✓ | ✓ | ✓ | Mitochondrial activation; morning emphasis |
| NR (NAD+) | ✓ | ✓ | ✓✓✓ | Evening for overnight sirtuin activation and repair |
| Creatine | ✓✓✓ | ✓✓ | ✓ | Primary morning/midday; no sleep interference |
| B-Vitamins | ✓✓✓ | ✓✓ | ✓ | Energy cofactors; B6 evening for GABA synthesis |
| Omega-3 (DHA/EPA) | ✓ | ✓✓✓ | ✓ | Structural; timing less critical; with food |
Cross-System Synergy Architecture
Synergy Network 1: Cholinergic Amplification
Synergy Network 1: Cholinergic Amplification
The Cholinergic Stack
Acetylcholine is the master neurotransmitter of cognition — governing memory formation, sustained attention, and learning. The NTRPX Meta System™ provides comprehensive cholinergic support through multiple synergistic mechanisms.Why This Architecture?
| Design Decision | Rationale |
|---|---|
| CDP-Choline for daily use | Provides BOTH choline AND uridine; lower TMAO risk than Alpha-GPC; safe for chronic use |
| Alpha-GPC for Sprint™ only | 2021 study showed 46% increased stroke risk with 10+ year use; reserved for acute/occasional |
| Huperzine A for Sprint™ only | Potent AChE inhibitor; 24h half-life; would accumulate with daily use |
| PS in Sustain™ | Membrane support complements choline supply; cortisol modulation aids sustained performance |
| Lion’s Mane in Boost™ | NGF stimulation supports long-term cholinergic neuron health; morning dosing standard |
Synergy Network 2: Mitochondrial Optimization
Synergy Network 2: Mitochondrial Optimization
The Bioenergetic Stack
Mitochondria are the powerhouses of every cell. The NTRPX Meta System™ addresses both mitochondrial biogenesis (creating MORE mitochondria) and mitochondrial function (making EXISTING mitochondria work better), plus ATP buffering for immediate availability.The PQQ + CoQ10 + Creatine + Cordyceps Mega-Stack
| Component | Role | Timing |
|---|---|---|
| PQQ | Creates new mitochondria (biogenesis via PGC-1α) | Morning (Boost™) |
| CoQ10 | Makes existing mitochondria work better (electron transport) | Morning (Boost™) |
| Cordyceps | Improves oxygen utilization; AMPK activation | Daytime (Sol™) |
| Creatine | Buffers ATP for instant availability | Morning + Daytime (Boost™ + Sol™) |
| NR | Provides NAD+ for overnight mitochondrial maintenance | Evening (Recover™) |
| Apigenin | Inhibits CD38 to preserve NAD+ | Evening (Recover™ + Luna™) |
| B-vitamins | Essential cofactors for all energy pathways | All day (All Systems Go™) |
Synergy Network 3: Sleep Architecture
Synergy Network 3: Sleep Architecture
The Thermoregulatory Sleep Stack
The NTRPX Meta System™ does NOT rely on sedation for sleep. Instead, it leverages the body’s natural thermoregulatory sleep-onset mechanism plus GABAergic support for deep sleep architecture.Why Glycine at Exactly 3g is Non-Negotiable
| Dose | Effect | Evidence |
|---|---|---|
| < 3g | Insufficient hypothalamic signaling | Subtherapeutic |
| = 3g | Triggers measurable 0.3°C core temperature drop | Bannai et al. 2012; Inagawa et al. 2006 |
| > 3g | No additional benefit; waste | Dose-response plateaus |
Why NOT Melatonin?
| Problem | Explanation |
|---|---|
| Suppresses endogenous production | Long-term use reduces natural melatonin synthesis |
| Creates dependency | Users often need increasing doses |
| Doesn’t address architecture | Only affects onset, not deep sleep quality |
| Timing sensitivity | Wrong timing can shift circadian phase |
Synergy Network 4: Methylation Pathway
Synergy Network 4: Methylation Pathway
The One-Carbon Metabolism Stack
Methylation governs over 200 biochemical reactions including neurotransmitter synthesis, DNA repair, detoxification, and gene expression. The NTRPX Meta System™ provides complete methylation support using ONLY active/coenzyme forms.Why ONLY Active B-Vitamin Forms
| Vitamin | Excluded Form | Why Excluded | Included Form | Why Included |
|---|---|---|---|---|
| B6 | Pyridoxine HCl | Neurotoxicity risk; competitive inhibition of P5P | P5P | Direct coenzyme; no conversion |
| B9 | Folic acid | Requires 4-step conversion; MTHFR variants; masks B12 deficiency | L-5-MTHF (Quatrefolic®) | Already active; bypasses all variants |
| B12 | Cyanocobalamin | Requires conversion; cyanide moiety | Methylcobalamin + Adenosylcobalamin | Direct coenzymes; complete coverage |
| B2 | Riboflavin | Requires phosphorylation | R5P | Direct coenzyme |
Synergy Network 5: Nitric Oxide & Blood Flow
Synergy Network 5: Nitric Oxide & Blood Flow
The Vascular Support Stack
Cognitive performance depends on blood flow delivering oxygen and nutrients to the brain. The NTRPX Meta System™ optimizes nitric oxide production for enhanced perfusion.Why L-Citrulline Over L-Arginine
| Factor | L-Arginine | L-Citrulline |
|---|---|---|
| Oral bioavailability | ~20% (extensive first-pass) | ~80% |
| Plasma arginine increase | Modest, brief | Sustained, significant |
| Effective dose | 6-10g (GI distress) | 3-6g (well-tolerated) |
| NO production | Limited by arginase | Bypasses arginase |
| NTRPX Decision | ❌ Excluded | ✅ Included in Sol™ |
Synergy Network 6: Adaptogenic Stress Resilience
Synergy Network 6: Adaptogenic Stress Resilience
The HPA Axis Modulation Stack
Chronic stress degrades cognitive performance, depletes neurotransmitters, and disrupts sleep. The NTRPX Meta System™ employs a circadian-synchronized adaptogen strategy.Adaptogen Timing Strategy
| Adaptogen | Timing | Rationale |
|---|---|---|
| Salidroside/Rhodiola | Morning (Boost™, Sol™) | Activating; MAO-B inhibition extends dopamine; may interfere with sleep if evening |
| Cordyceps | Daytime (Sol™) | Energizing; oxygen efficiency; pairs with physical activity |
| Ashwagandha | Midday (Sustain™) | GABAergic properties; cortisol reduction; some find too sedating for morning |
| Bacopa | Midday (Sustain™) | Chronic nootropic; timing less critical; traditionally with food |
| Saffron | Midday (Sustain™) | Serotonergic; mood support during active hours |
| L-Theanine | Anytime, emphasize evening | Acutely calming; pairs with stimulants to smooth; concentrate evening for sleep |
Ingredient Interaction Matrix
Synergies, Redundancies, and Prevented Antagonisms
Synergies, Redundancies, and Prevented Antagonisms
Confirmed Synergistic Pairs in NTRPX
| Pair | Mechanism | Location |
|---|---|---|
| CDP-Choline + Uridine (endogenous) | Phosphatidylcholine synthesis; membrane + ACh | Boost™ + Sustain™ |
| PQQ + CoQ10 | Biogenesis + function; new + efficient mitochondria | Boost™ |
| Creatine + PQQ + CoQ10 | More mitochondria, working better, with ATP buffer | Boost™ + Sol™ |
| Paraxanthine + L-Theanine | Alert without anxious; smooth stimulation | ParaCaffeine +™ |
| Glycine + Magnesium | Thermoregulation + GABA; comprehensive sleep onset | Recover™ + Luna™ |
| Apigenin + NR | CD38 inhibition preserves NR-derived NAD+ | Recover™ |
| Salidroside + Tyrosine | MAO-B inhibition + DA precursor = extended DA | Boost™ |
| DHA + PS | Membrane fluidity synergy; receptor support | Sustain™ |
| Ashwagandha + Bacopa | Stress reduction + memory; complementary mechanisms | Sustain™ |
| L-Citrulline + B9/B12 | NO production + vascular protection | Sol™ + All Systems Go™ |
| Cordyceps + Creatine | Oxygen efficiency + ATP buffer; endurance stack | Sol™ |
Prevented Antagonisms
| Avoided Combination | Why It’s Bad | NTRPX Solution |
|---|---|---|
| High-dose B6 (pyridoxine) + Levodopa | Peripheral conversion reduces efficacy | P5P only; L-DOPA only in Sprint™ |
| Stimulants + High-dose GABAergics (same time) | Opposing effects waste both | Circadian separation |
| Iron + Polyphenols/Tannins | Absorption interference | No iron in NTRPX formulas |
| Alpha-GPC (chronic) + cardiovascular risk | 46% increased stroke risk long-term | CDP-Choline daily; Alpha-GPC Sprint™ only |
| Huperzine A (daily) | 24h half-life; accumulation | Sprint™ only (occasional) |
| Multiple strong stimulants | Overstimulation; anxiety | Paraxanthine replaces caffeine (cleaner) |
| Melatonin + endogenous production | Suppression; dependency | Glycine thermoregulation instead |
Intentional Redundancies (Reinforcement)
| “Redundancy” | Why It’s Intentional |
|---|---|
| Glycine in Recover™ AND Luna™ | Critical threshold (3g+) for thermoregulation; insurance |
| Magnesium in Recover™ AND Luna™ | Multiple forms for different functions; ensures adequacy |
| CDP-Choline in Boost™ AND Sustain™ | All-day cholinergic support; split dosing optimal |
| Creatine in Boost™ AND Sol™ | Loading/maintenance; multiple touchpoints improve compliance |
| L-Theanine in multiple products | Ubiquitously useful; smooths stimulants, aids sleep |
Usage Protocols
Protocol Tiers: Entry to Complete
Protocol Tiers: Entry to Complete
The NTRPX Meta System™ is modular by design.
Users can enter at any level and progress as desired. Each tier provides standalone value while building toward complete optimization.Protocol Specifications
| Tier | Products | Use Case | Expected Benefits |
|---|---|---|---|
| 1: Entry | Luna™ OR ParaCaffeine +™ OR Sol™ | Specific need; testing the system | Targeted improvement in sleep OR energy OR hydration |
| 2: Foundation | All Systems Go™ (Boost + Sustain + Recover) | Daily optimization | Complete circadian support; energy, cognition, sleep |
| 3: Enhanced | All Systems Go™ + Neuraldrink™ OR ParaCaffeine +™ | Serious optimization | Foundation + hydration/ATP OR additional clean energy |
| 4: Complete | All products as indicated | Maximum optimization | Full biological coverage across all 12 domains |
Daily Schedule: Complete Protocol
Daily Schedule: Complete Protocol
24-Hour Complete Protocol Schedule
| Time | Products | Ritual |
|---|---|---|
| 6:00-7:00 AM | BOOST™ | Upon waking, with light breakfast |
| 7:00-9:00 AM | SOL™ | First hydration; mix in 16-20oz water |
| 9:00-10:00 AM | (Optional: PARACAFFEINE +™) | If additional alertness needed; 90-120 min after waking |
| 12:00-2:00 PM | SUSTAIN™ | With lunch |
| 2:00-4:00 PM | SOL™ (second serving, optional) | Afternoon hydration; NO paraxanthine products after 2PM |
| 6:00-8:00 PM | LUNA™ | Evening hydration; begin wind-down |
| 8:30-9:30 PM | RECOVER™ | 30-60 minutes before bed |
| 10:00-11:00 PM | Sleep | Target 7-9 hours |
Event Day Protocol (Sprint™)
For high-demand cognitive events (presentations, exams, competitions):| Time | Modification |
|---|---|
| Morning | SPRINT™ replaces Boost™ |
| Midday | Sustain™ as normal (or skip if Sprint™ effects persist) |
| No ParaCaffeine +™ | Sprint™ contains caffeine; no stacking |
| Evening | Recover™ + Luna™ as normal (extra important for recovery) |
| Frequency | Maximum 1-2× per week; not for daily use |
Stacking Rules & Paraxanthine Management
Stacking Rules & Paraxanthine Management
Paraxanthine Daily Limits
Paraxanthine appears in multiple NTRPX products. Track total daily intake:| Product | Paraxanthine Content |
|---|---|
| Sustain™ | 100mg |
| Sol™ | 100mg |
| ParaCaffeine +™ | 100mg |
| Combination | Total | Assessment |
|---|---|---|
| Sustain™ alone | 100mg | ✅ Safe |
| Sustain™ + ParaCaffeine +™ | 200mg | ✅ Safe |
| Sustain™ + Sol™ | 200mg | ✅ Safe |
| Sustain™ + Sol™ + ParaCaffeine +™ | 300mg | ⚠️ Maximum; rare occasions only |
| Any paraxanthine after 2PM | Variable | ❌ Avoid; sleep interference |
What NOT to Combine
| Combination | Why Avoid |
|---|---|
| Sprint™ + ParaCaffeine +™ | Sprint™ contains caffeine; excessive stimulation |
| Sprint™ + Boost™ (same day) | Redundant; Sprint™ replaces Boost™ for that day |
| Sprint™ + evening products (same day) | Sprint™ may override evening wind-down; ensure sleep |
| Any stimulant after 2PM | Sleep is sacred; no exceptions |
| Huperzine A daily | Only in Sprint™; 24h half-life; would accumulate |
Product Specifications Overview
Detailed formulations for each product follow in the next document.All Systems Go™
Foundation System — Daily ProtocolThree circadian-synchronized formulations providing complete daily biological optimization.
- Boost™: Morning activation
- Sustain™: Daytime performance
- Recover™: Evening recovery
Neuraldrink™
Circadian Functional BeveragesPrecision-formulated hydration synchronized to circadian biology.
- Sol™: Daytime hydration + energy + NO
- Luna™: Nighttime hydration + sleep support
ParaCaffeine +™
Clean Daily StimulationCaffeine evolved. Paraxanthine with synergistic cofactors for sustainable, sleep-compatible energy.
- 2.2× A2A receptor affinity
- No anxiogenic metabolites
- Everyday use appropriate
Sprint™
Acute Peak PerformanceMaximum cholinergic + dopaminergic drive for high-stakes cognitive events.
- Alpha-GPC + Huperzine A
- Caffeine + L-DOPA support
- Occasional use only (1-2×/week)
Document Control
| Version | Date | Author | Changes |
|---|---|---|---|
| 2.0 | 2026-01-25 | NTRPX R&D | Complete Meta System architecture with all ingredients from site |