Ashwagandha (KSM-66)
This ingredient monograph is under development.
Overview
Ashwagandha is a calming adaptogen that reduces cortisol by ~27% via 11β-HSD1 inhibition. Supports stress resilience, reduces anxiety, and may support testosterone levels.Taxonomy Position
- Domain: Adaptogens & Herbal Modulators / Endocrine & Hormonal
- Category: Classic Adaptogens (4.1), HPA Axis (3.1)
- Subcategory: Cortisol Modulators
Key Properties
| Property | Effect |
|---|---|
| Cortisol | ↓ 27% |
| Anxiety | ↓ Significant |
| Testosterone | ↑ Modest |
| Character | Calming adaptogen |
| Active Compounds | Withanolides |
Extract Standardization
- KSM-66: Full-spectrum root extract, 5% withanolides
- Sensoril: Root + leaf extract, higher withanolide content